- cyclodextrin, sulfobutyl ethers, sodium salts regulatory process names 1 cas names 1 iupac names 2 trade names 2 other identifiers 1 print infocard open brief profile. the application of sulfobutyl ether beta cyclodextrin sodium. shape: white power. sodium sulfobutylether- beta- cyclodextrin is a newly researched and developed production of our company. c 42 h 70- n o 35 · ( c 4 h 8 o 3 sna) n. sulfobutyl- β- cyclodextrin. it is applied to injectable drugs to improve the solubility of difficult soluble drugs, can. molecular weight : n. sulfobutyl ether- beta- cyclodextrin sodium salt: cas no: : synonyms: sulfobutylated beta- cyclodextrin sodium salt; sodium sulfobutylether β- cyclodextrin; betadex sulfobutyl ether sodium; sulfobutyl ether b- cyclodextrin; sodium salts; sulfobutyl ethers; sbecd; excipient sbecd; structural formula: molecular formula: c42h70o35: molecular. synonyms: β- cyclodextrin sulfobutyl ethers sodium salts. more beta cyclodextrin sulfobutyl ether images.
recently, there have been reports abroad that remdesivir ( a drug formulated with sulfobutyl beta cyclodextrin sodium and currently approved in the united states for the treatment of covid- 19 patients) and hepatitis c virus ( hcv) drugs the combined effect of inhibiting sars- cov- 2 is increased by 10 t. commonly employed pharmaceutical cyclodextrins include β- cyclodextrin, hydroxyl propyl β- cyclodextrin, sulfobutyl ether β- cyclodextrin sodium salt, randomly methylated β- cyclodextrin, and branched β- cyclodextrin ( rasheed and vvns, ). betadex sulfobutyl ether sodium is white to off- white crytstalline powder. free 2- day shipping on millions of items. despite its use in commercially available drugs such as intravenous voriconazole, there is little known in the medical literature about the clinical pharmacology of the solubilizing agent, sulfobutylether- beta- cyclodextrin ( sbecd). qmy123 purity 95- 105% appearance white powder application pharm api melting pointboiling pointpackage 25kg/ drum brand qinmuchem pictures of sulfobutyl beta cyclodextrin sulfobutyl ether ether beta. view all manufacturers & suppliers of sulfobutyl ether beta- cyclodextrin sodium api with drug master files ( dmf), cep/ cos, japanese dmfs, written confirmation ( wc) details listed on pharmacompass. ziprasidone is an antipsychotic agent indicated primarily for the treatment of schizophrenia. chemical and physical description. sulfobutyl ether beta cyclodextrin sodium( sbecd) is a new type of anionic high soluble cyclodextrin derivatives.
an intramuscular dosage form of ziprasidone was developed using beta- cyclodextrin sulfobutyl ether ( sbecd) to solubilize the drug by complexation. reliable supplier. it can easily form non- covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate. this pharma grade cyclodextrin excipient is a general solubility. betadex sulfobutyl ether sodium. heptakis- o- ( 4- sulfobutyl) - beta- cyclodextrin. we are making, exporting and supplying sulfobutyl ether beta cyclodextrin with msds in xian, shaanxi, china. sodium sulfobutylether- beta- cyclodextrin is an important modified production of beta- cyclodextrin.
works well in lab. features and applications: sulfobutyl ether- beta- cyclodextrin sodium salt is a high water- soluble anionic cyclodextrin derivative. sodium sulfobutyl ether beta cyclodextrin available on the site are 95% to 99% pure and comes with distinct molecular weights. it could reduce the renal toxicity, moderate drug’ s hemolysis, control the. press release - report consultant - sulfobutylether- beta- cyclodextrin ( sbecd) marketincreasing the solubility and the bioavailability of pharma drugs with biophore, pfizer, asymchem. sulfobutyl ether- beta- cyclodextrin, sodium salts building a20. all compounds are very polar and acidic in nature, and are not retained by traditional reversed- phase chromatography.
comparative effects of sodium dodecyl sulfate and sulfobutyl ether- β- cyclodextrin as pseudostationary phases in the electrokinetic chromatographic separation of hydrophobic compounds. in tablet form, voriconazole is rapidly absorbed from the gastrointestinal tract. synonyms : betadex sulfobutyl ether sodium. beta- cyclodextrin sulfobutyl ether. hydroxypropyl- beta- cd · beta- cyclodextrin · call today for a quote! further, the effects of water- soluble cyclodextrin derivatives, such as 2- hydroxypropyl- beta- cyclodextrin ( hp- beta- cyd) and sulfobutyl ether of beta- cyclodextrin ( sbe- beta- cyd), on the hemolytic activity of dy- 9760e were studied.
cyclolab is the manufacturer and supplier of usp nf grade dexolvetm, a „ generic” captisol ( betadex sulfobutyl ether sodium, sulfobutyl ether beta cyclodextrin sodium, sbecd, sbebcd, sbe), developed and manufactured by cyclolab with a proprietary process under cgmp conditions. san pedro street gardena, ca 90248 laboratory chemicals, manufacture of substances label elements prepared date： section 2. product name: sulfobutyl etherbeta cyclodextrin sodium salt. responsive service. inclusion complexation of ziprasidone mesylate ( zm) with sbecd was studied by circular dichroism ( cd. 4 cm analytical anion- exchange column containing a l61 packing column type for the separation of β- cyclodextrin and sulfobutyl ether β- cyclodextrin.
this is a description of the dionex ionpac as11, analytical, 4 × 250 mm column. synonym: β- cyclodextrin sulfobutyl ethers sodium salts. it could include drug molecules to from covalent compounds so that increase the drug’ s solubility, stability, safety. zhiyuan biotechnology is one of the leading china hydroxypropyl- beta- cyclodextrin, sulfobutyl ether- beta- cyclodextrin sodium salt, hydroxypropyl- gamma- cyclodextrin, methyl - beta- cyclodextrin, betadex sulfobutyl ether sodium manufacturers and suppliers, as a professional company, we have productive factory, which is able to produce high- quality products at good price. unii- 2pp9364507. - cyclodextrin heptasulfobutyl ether sodium: common name english. average formula weight. sulfobutyl ether beta- cyclodextrin ( seβcd) is a cyclodextrin derivative synthesized by β- cyclodextrin and 1, 4- bs( 1, 4- butane sultone) ( cas. synonym: beta cyclodextrin sulfobutyl ether sodium. - cyclodextrin sulfobutyl ether sodium: common name english view: view. quality control of hplc & nmr.
due to the low solubility of β- cyclodextrin, long- term storage may lead to drug precipitation; and it is nephrotoxic and lacks flexibility in the application of parenteral administration, so it. beta- cyclodextrin sulfobutyl ether sodium salts. sodium sulfobutyl ether beta cyclodextrin are used for making medicines, ointments, supplements, etc, and are organically obtained from the sources. molecular weight. cyclodextrin sulfobutyl ether is sulfonated derivative of cyclodextrin. 2) possible impurities. is a high water- soluble anionic cyclodextrin derivative.
molecular formula: c 42 h 70- n o 35 ( c 4 h 8 o 3 s na) n. sulfobutyl ether β- cyclodextrin ( captisol( ® ) ) and methyl β- cyclodextrin enhance and stabilize fluorescence of aqueous indocyanine green j biomed mater res b appl biomater. sulfobutyl ether β- cyclodextrin sodium ( also called betadex sulfobutyl ether sodium) is a chemically modified β- cyclodextrin used as drug delivery system. european pharmacopoeia ( ep) reference standard. songjiang, shanghai, china 11 spectrum laboratory products inc. sulfobutyl ether beta cyclodextrin sodium ( betadex sulfobutyl ether sodium, sbe- β- cd ) is a new type of anionic high soluble cyclodextrin derivatives. the cyclodextrin molecules contain a hydrophilic external surface and a lipophilic internal cavity. ( in 100 cm 3 solvent, at 25 ° c). research & manufacturing driven, quality beta- cyclodextrin and derivatives. sulfobutyl beta cyclodextrin.
it is one of the most popular excipients ever used in our. other names: b- cyclodextrin sulfobutyl ether sodium salt, β- cyclodextrin sulfobutyl ether, sulfobutylated beta- cyclodextrin sodium salt, sbecd, sbebcd. sulfobutyl ether- beta- cyclodextrin | c50h84na2o41s2 | cidstructure, chemical names, physical and chemical properties, classification, patents, literature. 0% on the anhydrous beta cyclodextrin sulfobutyl ether sodium [ ]. beta cyclodextrin sulfobutyl ethers, sodium salts; acceptance criteria: 95.
4- hydroxybutane- 1- sulfonic acid sodium salt, bis ( 4- sulfobutyl) ether disodium, residual beta- cyclodextrin. although bioavailability is near 100%, steady- state plasma concentrations are achieved more rapidly with an intravenous loading dose. check out alpha- cyclodextrin on ebay. hazards identification.
it could include drug molecules to from covalent compounds so that increase the drug’ s stability, solubility, safety. substance identity. beta- cyclodextrin sulfobutyl ether [ mi] sulfobutylether beta- cyclodextrin free acid. beta- cyclodextrin, sulfobutyl ethers. research use only. 3802 lane shengang road. voriconazole is available as a tablet and parenteral solution that uses sulfobutyl ether- β- cyclodextrin ( se- β- cd) as a solubilizer.
basis definition impurities betadex sulfobutyl ether sodium is prepared by alkylation of• heavy metals, method ii 〈 231〉 beta cyclodextrin sulfobutyl ether : nmt 5 ppm betadex using 1, 4- butane sultone under basic. average molecular formula. the usp betadex sulfobutyl ether sodium monograph describes a 25 × 0. com offers a comprehensive line of. journal of chromatography a 1999,, 53- 58. product description. this paper summarizes all known data on sbecd pharmacokinetics and s.
chemical and physical description. no membership fee. customer service. the degree of sulfobutylation varies, and the compound is a mixture of several components. betadex sulfobutyl ether sodium salt. beta- cyclodextrin sulfobutyl ether, sodium salt.
product name: sulfobutyl ether beta cyclodextrin synonym: sulfobutyl ether beta cyclodextrin salt cas noother names sulfobutyl ether beta cyclodextrin molecular formula c42h70o35 einecs no. ec number: | cas number:. - cyclodextrin, sulfobutyl beta cyclodextrin sulfobutyl ether ethers, sodium salts recommended related beta cyclodextrin sulfobutyl ether products more information if you have any enquiry about quotation or cooperation, please feel free to email us at com or use the following enquiry form. molecular weight: 2242. betadex sulfobutyl ether sodium salt is the sulfonated modified sodium salt of beta cyclodextrin, which is an anionic, highly water- soluble cyclodextrin derivative, can be well incorporated with drug molecules to form non- covalent complexes, thereby improving the stability, water solubility and safety of the drug, reducing nephrotoxicity, ease. fill your cart with color today! separation was achieved on an obelisc n column in anion- exchange. details as given below: - 1.